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Chang Chen Selected Research

Therapeutics

3/2024Magnetic modulation of lysosomes for cancer therapy.
1/2024Transcriptomic signatures of individual cell types in cerebral cavernous malformation.
11/2023Key role of exosomes derived from M2 macrophages in maintaining cancer cell stemness (Review).
10/2023Signaling metabolite succinylacetone activates HIF-1α and promotes angiogenesis in GSTZ1-deficient hepatocellular carcinoma.
8/2023Surgical resection following therapy with anlotinib in locally advanced papillary thyroid carcinoma: a case description.
7/2023Could BMMNCs therapy reduce the mid- and long-term rate of total hip arthroplasty of femoral head necrosis?: A systematic review and meta-analysis.
6/2023Analysis of the metastatic mechanism and progress in the treatment of breast cancer liver metastasis: a narrative review.
1/2023The IASLC grading system for invasive pulmonary adenocarcinoma: a potential prognosticator for patients receiving neoadjuvant therapy.
1/2023Targeting CXCR1 alleviates hyperoxia-induced lung injury through promoting glutamine metabolism.
1/2023Pharmacological boosting of cGAS activation sensitizes chemotherapy by enhancing antitumor immunity.
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Chang Chen Research Topics

Disease

92Neoplasms (Cancer)
04/2024 - 09/2003
39Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2024 - 09/2010
28Inflammation (Inflammations)
05/2024 - 10/2009
23Adenocarcinoma of Lung
03/2024 - 01/2017
22Lung Neoplasms (Lung Cancer)
03/2024 - 07/2009
18Neoplasm Metastasis (Metastasis)
06/2023 - 05/2006
16Infections
08/2023 - 05/2009
12Breast Neoplasms (Breast Cancer)
04/2024 - 06/2014
12Body Weight (Weight, Body)
08/2022 - 01/2011
11Cognitive Dysfunction
12/2023 - 04/2015
10Hepatocellular Carcinoma (Hepatoma)
12/2023 - 01/2020
9Hyperplasia
12/2023 - 08/2010
9Hypoxia (Hypoxemia)
10/2023 - 10/2017
8Necrosis
11/2023 - 09/2015
8Fibrosis (Cirrhosis)
11/2023 - 01/2011
8Parkinson Disease (Parkinson's Disease)
01/2022 - 09/2016
7Neuroinflammatory Diseases
04/2024 - 11/2012
7Liver Cirrhosis (Hepatic Cirrhosis)
11/2023 - 07/2018
7Adenocarcinoma
01/2023 - 07/2016
7Acute Lung Injury
12/2019 - 06/2006
6Lung Injury
05/2024 - 06/2006
6Ischemic Stroke
11/2023 - 09/2013
6Carcinogenesis
10/2023 - 05/2017
6Pain (Aches)
07/2023 - 01/2014
6Neurodegenerative Diseases (Neurodegenerative Disease)
06/2023 - 07/2004
6Atherosclerosis
04/2023 - 04/2014
6Hemorrhage
03/2023 - 04/2008
6Lung Diseases (Lung Disease)
11/2022 - 04/2011
6Type 2 Diabetes Mellitus (MODY)
08/2022 - 07/2010
6Fistula
02/2022 - 11/2009
5Thrombosis (Thrombus)
04/2024 - 01/2015
5COVID-19
01/2023 - 01/2021
5Brain Ischemia (Cerebral Ischemia)
01/2022 - 01/2013
4Pneumonia (Pneumonitis)
05/2024 - 11/2009
4Lymphatic Metastasis
12/2023 - 01/2020
4Primary Graft Dysfunction
01/2023 - 03/2020
4Hyperoxia
01/2023 - 01/2018
4Cholestasis
11/2022 - 01/2015
4Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 08/2010
4Myocardial Infarction
01/2022 - 02/2014
4Non-alcoholic Fatty Liver Disease
01/2020 - 03/2013
4Cardiomegaly (Heart Hypertrophy)
01/2018 - 04/2010
3Sepsis (Septicemia)
05/2024 - 03/2011
3Chronic Obstructive Pulmonary Disease (COPD)
01/2024 - 01/2018
3Heart Failure
01/2024 - 09/2017

Drug/Important Bio-Agent (IBA)

30Biomarkers (Surrogate Marker)IBA
11/2023 - 09/2013
29Proteins (Proteins, Gene)FDA Link
11/2023 - 07/2004
12xylometazoline (stas)IBA
03/2024 - 01/2017
12Glucose (Dextrose)FDA LinkGeneric
11/2023 - 01/2018
11RNA (Ribonucleic Acid)IBA
03/2023 - 10/2019
11LipidsIBA
01/2023 - 03/2013
10Bile Acids and Salts (Bile Acids)IBA
04/2024 - 11/2015
10EnzymesIBA
11/2023 - 09/2013
8CytokinesIBA
04/2023 - 09/2010
8Oxygen (Dioxygen)IBA
01/2023 - 05/2004
8Messenger RNA (mRNA)IBA
01/2022 - 02/2005
7Sevoflurane (Ultane)FDA LinkGeneric
01/2024 - 01/2020
6Therapeutic UsesIBA
01/2023 - 01/2015
5Histones (Histone)IBA
05/2024 - 01/2020
5InflammasomesIBA
05/2024 - 02/2013
5LigandsIBA
10/2023 - 05/2009
5MicroRNAs (MicroRNA)IBA
03/2023 - 10/2014
5Aspartate Aminotransferases (Aspartate Transaminase)IBA
11/2022 - 12/2016
5Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022 - 07/2010
5Neuroprotective AgentsIBA
01/2021 - 01/2019
5Matrix Metalloproteinases (MMPs)IBA
01/2021 - 01/2018
5DNA (Deoxyribonucleic Acid)IBA
01/2020 - 06/2015
4Toll-Like Receptor 4IBA
04/2024 - 05/2009
4ErbB Receptors (EGF Receptor)IBA
11/2023 - 01/2018
4Carbon Tetrachloride (Tetrachloromethane)IBA
11/2023 - 01/2018
4Prostaglandins DIBA
01/2023 - 03/2020
4PlatinumIBA
01/2023 - 05/2013
4Indicators and Reagents (Reagents)IBA
01/2023 - 01/2019
4Carcinoembryonic AntigenIBA
01/2023 - 07/2016
4Interleukin-6 (Interleukin 6)IBA
07/2021 - 03/2011
4CateninsIBA
04/2021 - 11/2015
4echinacosideIBA
01/2021 - 01/2019
4Hormones (Hormone)IBA
07/2020 - 01/2017
4oxidized low density lipoproteinIBA
10/2017 - 01/2016
4CholesterolIBA
10/2017 - 02/2005
4Amino AcidsFDA Link
01/2016 - 03/2013
4Heme Oxygenase-1IBA
06/2011 - 04/2008
3LipopolysaccharidesIBA
04/2024 - 06/2006
3Immune Checkpoint InhibitorsIBA
03/2024 - 01/2020
3PowdersIBA
02/2024 - 10/2007
3Cell-Free Nucleic AcidsIBA
11/2023 - 01/2021

Therapy/Procedure

37Therapeutics
03/2024 - 10/2007
12Drug Therapy (Chemotherapy)
03/2024 - 07/2009
11Thoracotomy
02/2022 - 09/2010
10Immunotherapy
05/2024 - 01/2020
9Neoadjuvant Therapy
03/2024 - 07/2009
9Pneumonectomy (Lung Volume Reduction)
01/2022 - 11/2009
8Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2024 - 10/2007
7Adjuvant Chemotherapy
12/2023 - 09/2018
6Segmental Mastectomy (Lumpectomy)
03/2024 - 10/2016
6Lung Transplantation
09/2023 - 04/2011
6Lymph Node Excision (Lymph Node Dissection)
01/2021 - 05/2006
5Radiotherapy
06/2023 - 11/2009
4Length of Stay
08/2023 - 01/2014
4Artificial Respiration (Mechanical Ventilation)
01/2021 - 02/2014